SCI 363 Molecular Pathology and Genetics

Content

This course comprises selected topics from general and molecular pathology and  human (molecular) genetics.  This includes cell injury and cell death, acute and chronic inflammation, tissue repair, regeneration and fibrosis, hemodynamic disorders and  thrombosis, diseases of immunity, general pathology of infectious diseases, neoplasia, chromosome structure and function, genes in pedigrees and populations, human gene expression, functional genomics, instability of the human genome, genetic mapping of Mendelian characters, identification of human disease genes and molecular pathology:from gene to disease.

Instructor

Prof. Dr. Cees Cornelisse

Track

Biomedical Science

Period

Fall / 2008

Course Material

Essential:

• Basic Pathology, V. Kumar, R.S. Cotran & S.L. Robbins, 7th, edition(ISBN hardcover 07-7216-9274-5,Saunders
• Human Molecular Genetics, T. Strachan & A.P. Read 3d edition, Garland Science, ISBN 0-8153-4184-9

 Recommended:

• Alberts et al., Molecular Biology of the Cell, 4th edition, Garland Science ,  ISBN 0-8153-4072-9
• Clinical Medicine, P.Kumar &  M. Clark, 5th edition, ISBN 0 70202606 9 (International Student Edition)
• Biochemistry, JM Berg, JL, Tymoczko, L. Stryer, 6thNew York, ISBN 97807167664,, hard cover edition, W.H. Freeman,

Prerequisites

The following courses are required in order to take this course:

• SCI 131 Introduction to Life Science
• SCI 191 Introductory Science Laboratory
• SCI 226 Biochemistry

Additional Prerequisites

• Recommended: AC110, AC120, AC130, SCI231,SCI133
• Required for: SCI365, SCI337,SCI332
• Other courses that are relevant to this course: SCI261, SCI262,SCI291